Fill a skillet to about 1" up the sides with canola oil. Line a baking sheet with paper towels.
Rinse the shrimp and pat dry. Toss them into the wet batter and let them hang out in there for about 10 minutes or so. Then toss them into the Panko crumbs and let them hang out there for another 10 minutes. The wait time allows the batter and crumbs to really stick onto the shrimp.
While your shrimp is hanging around in the batter and seasonings, heat up the oil in the skillet. Heat to shimmering, but not smoking. Be sure to let the oil get hot enough to shimmer or the shrimp will stick to the bottom of the skillet.
Carefully drop the battered and breaded shrimp into the hot oil and fry for about 2-3 minutes then flip and fry on the other side for another minute until golden brown.
Remove fried shrimp to paper towel-lined baking sheet.